BD4 (DEFB104A) (3-39) Mouse Monoclonal Antibody [Clone ID: L13-10-D1]

CAT#: AM02223PU-N

BD4 (DEFB104A) (3-39) mouse monoclonal antibody, clone L13-10-D1, Purified

Product Images

Immunohistochemistry of beta-Defensin-4 staining in Paraffin section of peritonsilar abscess. Antigen retrieval was performed with Trypsin. The sections were incubated with AM02223PU (1/75) and detected using Histostain Plus Broad Kit. AM02223PU stains abscess formatin (AF), surface epithelium (SE), crypt epithelium (CE) and lymphatic folicules (LF). Original magnification: x2. Schwaab M et al. (2009) Eur J Clin Microbiol Infect Dis 28 (7): 745-755.

Specifications

Product Data

• Clone Name: L13-10-D1
• Applications: ELISA, IHC, R, WB
• Recommended Dilution: RIA.
  ELISA.
  Western blot.
  Immunohistochemistry on Paraffin Sections: 1 µg/ml (Ref.1).
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Synthetic Human beta-Defensin 4 (aa 3-39)
• Specificity: This antibody detects Human beta-Defensin 4 (aa 3-39).
  There was cross reactivity obtained with Human beta-Defensin 1, beta-Defensin 2 and beta-Defensin 3.
• Formulation: 50mM TRIS pH 7,4
  State: Purified
  State: Lyophilized purified Cell Culture Supernatant
• Reconstitution Method: Restore in aqua bidest to 1 mg/ml.
• Purification: Protein G Chromatography
• Conjugation: Unconjugated
• Storage: Store lyophilized at 2-8°C and reconstituted at -20°C.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: One year from despatch.
• Gene Name: defensin beta 104A
• Database Link:
  Entrez Gene 140596 Human
  UniProt ID Q8WTQ1
• Background: Beta 4 Defensin has antimicrobial activity and synergistic effects with lysozyme and DEFB103. High expression levels are seen in the testis. Gastric antrum also exhibits relativey high levels. A lower exppression is observed in uterus and neutrophils thyroid gland, lung, and kidney. No detectable expression was observed in other tissues tested. Antimicrobial activity is decreased when the sodium chloride concentration is increased. Beta 4 Defensin belongs to the beta-defensin family.
• Synonyms: DEFB104A, DEFB104B, DEFB4, Beta-defensin 4, BD-4, hBD-4, DEFB-4, DEFB104
• Note: LocusID 140596