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Target Symbol
- CD59 (23)
- ALPHA 1 ANTITRYPSIN (22)
- ISOCITRATE DEHYDROGENASE (19)
- NAT1 (17)
- CACNB2 (16)
- AKT1 (14)
- TCF7L2 (14)
- TGIF (14)
- EGFR (13)
- IDH2 (13)
- IRF5 (13)
- TGIF1 (13)
- B RAF (12)
- ING1 (12)
- ABLIM2 (11)
- BIN1 (11)
- CAMKK2 (11)
- FGFR1 (11)
- GBA (11)
- NF2 (11)
- RAD51 (11)
- TRIM72 (11)
- WTAP (11)
- ZFYVE27 (11)
- BAIAP2 (10)
- CAMK2B (10)
- CD33 (10)
- FGFR4 (10)
- HMGA1 (10)
- IKZF3 (10)
- MAP2 (10)
- MME (10)
- NDRG2 (10)
- PALM2AKAP2 (10)
- PAX2 (10)
- PRKAR1B (10)
- RUNX1T1 (10)
- SERPINA1 (10)
- SIGLEC6 (10)
- XRCC3 (10)
- BANP (9)
- CD8A (9)
- ERG (9)
- FOXM1 (9)
- HER2 (9)
- MALT1 (9)
- NRG1 (9)
- NUMB (9)
- PPP2R2B (9)
- RGS3 (9)
- STAT1 (9)
- ABL2 (8)
- ALKALINE PHOSPHATASE (8)
- AP2B1 (8)
- BAD (8)
- CASP7 (8)
- CD10 (8)
- CDC42 (8)
- COASY (8)
- DYSTROPHIN (8)
- FGR (8)
- FHL2 (8)
- GGA1 (8)
- HFE (8)
- IL1RA (8)
- IMPDH1 (8)
- JNK1 (8)
- LAMC2 (8)
- M-CSF (8)
- MBNL1 (8)
- MET (8)
- MUTYH (8)
- NCALD (8)
- NDOR1 (8)
- PAX8 (8)
- PCBP2 (8)
- PDE4D (8)
- PDLIM2 (8)
- PPAR GAMMA (8)
- STAU2 (8)
- XBP1 (8)
- ADIPONECTIN (7)
- ALPHA SYNUCLEIN (7)
- APOLIPOPROTEIN E (7)
- ARSA (7)
- ATF3 (7)
- BCAT1 (7)
- BCL2 (7)
- CCM2 (7)
- CD36 (7)
- CERKL (7)
- CHAC1 (7)
- CNOT4 (7)
- CSTF1 (7)
- DDR2 (7)
- DGKA (7)
- ERBB 3 (7)
- EZH2 (7)
- FGFR2 (7)
- FHL1 (7)
Species
- Human (25379)
- Mouse (380)
- SARS-CoV-2 (19)
- Escherichia coli (12)
- Blomia tropicalis (10)
- Dermatophagoides pteronyssinus (6)
- Streptococcus Pyogenes (5)
- Staphylococcus aureus (4)
- Dermatophagoides farinae (2)
- Rabbit (2)
- Streptococcus sp. (2)
- Alternaria alternata (1)
- Betula pendula (1)
- Chlorocebus aethiops (1)
- Cynomolgus (1)
- Drosophila melanogaster (1)
- Enterobacteria phage T4 (1)
- Escherichia phage T7 (1)
- HIV (1)
- Human herpesvirus (1)
- Human papillomavirus (1)
- Humulus japonicus (1)
- Lachnospiraceae bacterium ND2006 (1)
- Lepidoglyphus destructor (1)
- Leptotrichia wadei (1)
- Macaca fascicularis (1)
- Mucor hiemalis (1)
- Mus musculus (1)
- Proteobacteria (1)
- SIV (1)
- Serratia marcescens (1)
- Staphylococcus aureus subsp. (1)
- Streptomyces plicatus (1)
Expression Hosts
Tags
- C-Myc/DDK (22214)
- N-His (2025)
- N-GST and C-His (433)
- C-MYC/DDK (339)
- C-DDK (196)
- N-GST and C-HIS (148)
- C-DDK/His (94)
- Tag Free (65)
- C-His (63)
- N-His-ABP (Albumin-Binding Protein) (52)
- C-HIS (47)
- Myc-DDK (40)
- C-Fc (26)
- N-His-Trx (17)
- N-GST, C-His (13)
- N-GST (7)
- N-HIS (7)
- N-His PDCD1(Pro21-Val170) (5)
- N-His/DDK (5)
- N-His-GST (4)
- C-Fc/His (3)
- His-tag (3)
- N-DDK (3)
- C-DDK-His (2)
- C-Myc-DDK (2)
- N-GFP (2)
- N-His-PDCD1(Pro21-Val170) (2)
- N-terminal His (2)
- N-terminal His-PDCD1(Pro21-Val170) tag (2)
- C-6His (1)
- C-DDK/10xHis (1)
- C-FC (1)
- C-Fc Human (1)
- C-Fc Mouse (1)
- C-HIS/C (1)
- C-His/AVIplus (1)
- C-His/DDK (1)
- C-Mouse Fc and 6×His (1)
- C-terminal DDK (1)
- His tag (1)
- N-10*His (1)
- N-AVI (1)
- N-DDK/His (1)
- N-FUSION (1)
- N-GST(CKM) and N-His(CKB) (1)
- N-HIS and C-AVIPLUS (1)
- N-PROTEIN (1)
- N-TRX (1)
- N-TRXA (1)
- N-Trx-His (1)
- N-terminal murine Fc Tag (1)
Protein Source
Mutants
QC Levels
Families
- Druggable Genome (12347)
- Transmembrane (5317)
- Transcription Factors (3048)
- Secreted Protein (2337)
- Protein Kinase (1301)
- ES Cell Differentiation/IPS (1007)
- Protease (808)
- Stem cell - Pluripotency (743)
- Phosphatase (319)
- GPCR (305)
- Adult stem cells (260)
- Embryonic stem cells (189)
- Ion Channels: Other (184)
- Nuclear Hormone Receptor (160)
- Cancer stem cells (128)
- Induced pluripotent stem cells (106)
- P450 (106)
- Ion Channels: Potassium (86)
- Stem cell relevant signaling - JAK/STAT signaling pathway (80)
- Stem cell relevant signaling - TGFb/BMP signaling pathway (79)
- Stem cell relevant signaling - Wnt Signaling pathway (60)
- Stem cell relevant signaling - DSL/Notch pathway (50)
- Ion Channels: Transient receptor potential (33)
- Ion Channels: Cys-loop Receptors (25)
- Ion Channels: Glutamate Receptors (24)
- Ion Channels: ATP Receptors (17)
- Ion Channels: Sodium (11)
- Ion Channels: Calcium (5)
- Ion Channels: Cyclic nucleotide gated (5)
Pathways
- Metabolic pathways (1987)
- Pathways in cancer (1036)
- MAPK signaling pathway (744)
- Cytokine-cytokine receptor interaction (613)
- Focal adhesion (562)
- Regulation of actin cytoskeleton (510)
- Endocytosis (450)
- Chemokine signaling pathway (438)
- Neurotrophin signaling pathway (425)
- Wnt signaling pathway (380)
- Insulin signaling pathway (365)
- Jak-STAT signaling pathway (353)
- Calcium signaling pathway (331)
- ErbB signaling pathway (330)
- Prostate cancer (330)
- Alzheimer's disease (325)
- Cell cycle (324)
- Neuroactive ligand-receptor interaction (319)
- T cell receptor signaling pathway (317)
- Axon guidance (312)
- Hematopoietic cell lineage (312)
- Natural killer cell mediated cytotoxicity (312)
- Colorectal cancer (303)
- Tight junction (300)
- Toll-like receptor signaling pathway (300)
- Pancreatic cancer (297)
- Cell adhesion molecules (CAMs) (294)
- Apoptosis (292)
- Purine metabolism (290)
- Huntington's disease (285)
- Leukocyte transendothelial migration (282)
- Progesterone-mediated oocyte maturation (282)
- Ubiquitin mediated proteolysis (275)
- Oocyte meiosis (266)
- Adherens junction (263)
- Melanoma (256)
- GnRH signaling pathway (255)
- Chronic myeloid leukemia (249)
- Fc gamma R-mediated phagocytosis (248)
- Melanogenesis (246)
- Small cell lung cancer (241)
- Renal cell carcinoma (230)
- Fc epsilon RI signaling pathway (229)
- TGF-beta signaling pathway (229)
- Glioma (225)
- Dilated cardiomyopathy (224)
- Acute myeloid leukemia (222)
- B cell receptor signaling pathway (222)
- VEGF signaling pathway (219)
- Vascular smooth muscle contraction (217)
- Endometrial cancer (216)
- Hypertrophic cardiomyopathy (HCM) (214)
- Lysosome (210)
- Gap junction (207)
- p53 signaling pathway (207)
- Non-small cell lung cancer (206)
- Adipocytokine signaling pathway (204)
- Complement and coagulation cascades (199)
- Systemic lupus erythematosus (198)
- NOD-like receptor signaling pathway (188)
- PPAR signaling pathway (188)
- Epithelial cell signaling in Helicobacter pylori infection (186)
- Arrhythmogenic right ventricular cardiomyopathy (ARVC) (178)
- Parkinson's disease (178)
- Long-term depression (175)
- Pathogenic Escherichia coli infection (174)
- Spliceosome (173)
- Antigen processing and presentation (172)
- RIG-I-like receptor signaling pathway (172)
- Bladder cancer (170)
- Pyrimidine metabolism (169)
- Amyotrophic lateral sclerosis (ALS) (168)
- Long-term potentiation (164)
- Olfactory transduction (163)
- Glycolysis / Gluconeogenesis (159)
- Viral myocarditis (158)
- ECM-receptor interaction (154)
- mTOR signaling pathway (146)
- Thyroid cancer (145)
- Oxidative phosphorylation (141)
- Arginine and proline metabolism (139)
- Cytosolic DNA-sensing pathway (135)
- Phosphatidylinositol signaling system (135)
- Ribosome (133)
- Type II diabetes mellitus (132)
- Cardiac muscle contraction (130)
- Hedgehog signaling pathway (126)
- Basal cell carcinoma (125)
- Valine (122)
- Drug metabolism - cytochrome P450 (121)
- Glutathione metabolism (120)
- Metabolism of xenobiotics by cytochrome P450 (120)
- Tryptophan metabolism (114)
- Type I diabetes mellitus (113)
- Vibrio cholerae infection (113)
- Glycerophospholipid metabolism (111)
- leucine and isoleucine degradation (111)
- Autoimmune thyroid disease (107)
- Inositol phosphate metabolism (106)
- Drug metabolism - other enzymes (103)
- Tyrosine metabolism (101)
- Alanine (99)
- aspartate and glutamate metabolism (99)
- Fatty acid metabolism (98)
- Amino sugar and nucleotide sugar metabolism (97)
- Arachidonic acid metabolism (97)
- Notch signaling pathway (97)
- Glycerolipid metabolism (95)
- Retinol metabolism (95)
- Lysine degradation (94)
- RNA degradation (94)
- Graft-versus-host disease (92)
- Allograft rejection (89)
- Fructose and mannose metabolism (89)
- Nucleotide excision repair (88)
- Primary immunodeficiency (88)
- Pyruvate metabolism (87)
- Proteasome (86)
- Prion diseases (85)
- Citrate cycle (TCA cycle) (84)
- Base excision repair (83)
- Starch and sucrose metabolism (82)
- Propanoate metabolism (74)
- Butanoate metabolism (72)
- Histidine metabolism (72)
- Cysteine and methionine metabolism (70)
- Nitrogen metabolism (68)
- Glycine (67)
- Sphingolipid metabolism (67)
- serine and threonine metabolism (67)
- Androgen and estrogen metabolism (66)
- Dorso-ventral axis formation (66)
- Regulation of autophagy (62)
- DNA replication (61)
- Taste transduction (61)
- Ether lipid metabolism (60)
- beta-Alanine metabolism (60)
- Maturity onset diabetes of the young (59)
- Porphyrin and chlorophyll metabolism (59)
- Homologous recombination (58)
- Pentose phosphate pathway (58)
- Linoleic acid metabolism (57)
- Aminoacyl-tRNA biosynthesis (55)
- Phenylalanine metabolism (54)
- SNARE interactions in vesicular transport (54)
- Asthma (53)
- Galactose metabolism (53)
- Selenoamino acid metabolism (49)
- Nicotinate and nicotinamide metabolism (47)
- Renin-angiotensin system (45)
- Mismatch repair (44)
- Basal transcription factors (43)
- Primary bile acid biosynthesis (43)
- Biosynthesis of unsaturated fatty acids (41)
- Sulfur metabolism (39)
- Ascorbate and aldarate metabolism (36)
- N-Glycan biosynthesis (36)
- Pantothenate and CoA biosynthesis (36)
- Limonene and pinene degradation (35)
- One carbon pool by folate (34)
- RNA polymerase (34)
- Riboflavin metabolism (34)
- Glycosaminoglycan degradation (33)
- O-Glycan biosynthesis (33)
- Other glycan degradation (32)
- alpha-Linolenic acid metabolism (32)
- ABC transporters (31)
- Glyoxylate and dicarboxylate metabolism (31)
- C21-Steroid hormone metabolism (30)
- Circadian rhythm - mammal (30)
- Caffeine metabolism (29)
- Terpenoid backbone biosynthesis (29)
- Folate biosynthesis (28)
- Glycosphingolipid biosynthesis - lacto and neolacto series (28)
- Pentose and glucuronate interconversions (28)
- Non-homologous end-joining (26)
- Heparan sulfate biosynthesis (24)
- Chondroitin sulfate biosynthesis (23)
- Taurine and hypotaurine metabolism (23)
- Keratan sulfate biosynthesis (21)
- leucine and isoleucine biosynthesis (21)
- Glycosphingolipid biosynthesis - globo series (20)
- Fatty acid elongation in mitochondria (18)
- Steroid biosynthesis (18)
- Thiamine metabolism (18)
- Glycosphingolipid biosynthesis - ganglio series (17)
- Phenylalanine (16)
- tyrosine and tryptophan biosynthesis (16)
- Synthesis and degradation of ketone bodies (14)
- Cyanoamino acid metabolism (13)
- Methane metabolism (13)
- Glycosylphosphatidylinositol(GPI)-anchor biosynthesis (11)
- Ubiquinone and other terpenoid-quinone biosynthesis (11)
- Fatty acid biosynthesis (10)
- Vitamin B6 metabolism (10)
- D-Glutamine and D-glutamate metabolism (9)
- Lysine biosynthesis (8)
- Protein export (7)
- Biotin metabolism (3)
- D-Arginine and D-ornithine metabolism (2)
- Lipoic acid metabolism (2)
- O-Mannosyl glycan biosynthesis (1)