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- MEK1 (34)
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Antibody Hosts
Clonalities
Knockout (KO) Validation
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Families
- Druggable Genome (1926)
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- Stem cell relevant signaling - JAK/STAT signaling pathway (19)
- P450 (15)
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- Stem cell relevant signaling - TGFb/BMP signaling pathway (10)
- GPCR (9)
- Ion Channels: Other (9)
- Ion Channels: Cys-loop Receptors (3)
- Stem cell relevant signaling - Wnt Signaling pathway (3)
- Ion Channels: Potassium (2)
Pathways
- Metabolic pathways (451)
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- Regulation of actin cytoskeleton (128)
- T cell receptor signaling pathway (128)
- Pancreatic cancer (126)
- Acute myeloid leukemia (122)
- Renal cell carcinoma (122)
- Non-small cell lung cancer (121)
- Progesterone-mediated oocyte maturation (116)
- Glioma (115)
- Chronic myeloid leukemia (112)
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- Fc gamma R-mediated phagocytosis (101)
- GnRH signaling pathway (100)
- VEGF signaling pathway (99)
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- Natural killer cell mediated cytotoxicity (89)
- Purine metabolism (78)
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- Gap junction (74)
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- Wnt signaling pathway (72)
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- Oocyte meiosis (70)
- mTOR signaling pathway (67)
- Leukocyte transendothelial migration (66)
- Cell cycle (64)
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- Type II diabetes mellitus (62)
- Long-term potentiation (61)
- Prion diseases (61)
- Adherens junction (60)
- Jak-STAT signaling pathway (60)
- Arginine and proline metabolism (59)
- Long-term depression (59)
- Glycolysis / Gluconeogenesis (58)
- Alzheimer's disease (56)
- Vascular smooth muscle contraction (56)
- Ubiquitin mediated proteolysis (53)
- Amyotrophic lateral sclerosis (ALS) (52)
- Nucleotide excision repair (50)
- Valine (50)
- leucine and isoleucine degradation (50)
- Dorso-ventral axis formation (49)
- Phosphatidylinositol signaling system (47)
- Tight junction (46)
- Epithelial cell signaling in Helicobacter pylori infection (44)
- Parkinson's disease (42)
- Adipocytokine signaling pathway (41)
- Axon guidance (41)
- Calcium signaling pathway (41)
- Inositol phosphate metabolism (41)
- Pathogenic Escherichia coli infection (41)
- DNA replication (39)
- Fatty acid metabolism (39)
- RNA degradation (35)
- Butanoate metabolism (34)
- Huntington's disease (34)
- Mismatch repair (34)
- Spliceosome (34)
- Basal cell carcinoma (33)
- Base excision repair (32)
- Lysine degradation (32)
- Propanoate metabolism (32)
- TGF-beta signaling pathway (32)
- Alanine (30)
- aspartate and glutamate metabolism (30)
- p53 signaling pathway (30)
- Dilated cardiomyopathy (28)
- Hypertrophic cardiomyopathy (HCM) (28)
- Pyruvate metabolism (28)
- Arrhythmogenic right ventricular cardiomyopathy (ARVC) (27)
- Oxidative phosphorylation (26)
- Proteasome (26)
- Glycine (25)
- Primary immunodeficiency (25)
- serine and threonine metabolism (25)
- Cell adhesion molecules (CAMs) (24)
- Tyrosine metabolism (24)
- ABC transporters (23)
- Arachidonic acid metabolism (22)
- Hedgehog signaling pathway (22)
- One carbon pool by folate (22)
- Tryptophan metabolism (22)
- Glutathione metabolism (21)
- Pentose phosphate pathway (21)
- beta-Alanine metabolism (21)
- Cardiac muscle contraction (19)
- Cytokine-cytokine receptor interaction (19)
- Glycerolipid metabolism (19)
- NOD-like receptor signaling pathway (18)
- Notch signaling pathway (18)
- PPAR signaling pathway (18)
- Terpenoid backbone biosynthesis (18)
- Histidine metabolism (17)
- Starch and sucrose metabolism (17)
- Antigen processing and presentation (16)
- Drug metabolism - cytochrome P450 (16)
- Amino sugar and nucleotide sugar metabolism (15)
- Fatty acid elongation in mitochondria (15)
- Citrate cycle (TCA cycle) (14)
- RIG-I-like receptor signaling pathway (14)
- Vibrio cholerae infection (14)
- Cysteine and methionine metabolism (13)
- Lysosome (13)
- Metabolism of xenobiotics by cytochrome P450 (13)
- Neuroactive ligand-receptor interaction (13)
- Retinol metabolism (13)
- Circadian rhythm - mammal (12)
- Complement and coagulation cascades (12)
- Nicotinate and nicotinamide metabolism (12)
- Synthesis and degradation of ketone bodies (12)
- Folate biosynthesis (11)
- Fructose and mannose metabolism (11)
- Galactose metabolism (11)
- Maturity onset diabetes of the young (11)
- Renin-angiotensin system (11)
- SNARE interactions in vesicular transport (11)
- N-Glycan biosynthesis (10)
- Regulation of autophagy (10)
- Type I diabetes mellitus (10)
- Methane metabolism (9)
- RNA polymerase (9)
- Selenoamino acid metabolism (9)
- Systemic lupus erythematosus (9)
- ECM-receptor interaction (8)
- Hematopoietic cell lineage (8)
- Nitrogen metabolism (8)
- Porphyrin and chlorophyll metabolism (8)
- Ribosome (8)
- Cytosolic DNA-sensing pathway (7)
- Glyoxylate and dicarboxylate metabolism (7)
- Homologous recombination (7)
- Aminoacyl-tRNA biosynthesis (6)
- Sulfur metabolism (6)
- Viral myocarditis (6)
- Androgen and estrogen metabolism (5)
- Caffeine metabolism (5)
- Drug metabolism - other enzymes (5)
- Other glycan degradation (5)
- Pantothenate and CoA biosynthesis (5)
- Primary bile acid biosynthesis (5)
- Sphingolipid metabolism (5)
- Ascorbate and aldarate metabolism (4)
- Fatty acid biosynthesis (4)
- Glycerophospholipid metabolism (4)
- Vitamin B6 metabolism (4)
- Cyanoamino acid metabolism (3)
- Glycosaminoglycan degradation (3)
- Phenylalanine metabolism (3)
- Taurine and hypotaurine metabolism (3)
- D-Glutamine and D-glutamate metabolism (2)
- Ether lipid metabolism (2)
- Limonene and pinene degradation (2)
- Non-homologous end-joining (2)
- O-Glycan biosynthesis (2)
- Olfactory transduction (2)
- Steroid biosynthesis (2)
- Taste transduction (2)
- Thiamine metabolism (2)
- Basal transcription factors (1)
- Biosynthesis of unsaturated fatty acids (1)
- Glycosphingolipid biosynthesis - lacto and neolacto series (1)
- Keratan sulfate biosynthesis (1)
- Protein export (1)
- Riboflavin metabolism (1)
- leucine and isoleucine biosynthesis (1)