KCNK3 (NM_002246) Human Recombinant Protein

CAT#: TP762252

Purified recombinant protein of Human potassium channel, subfamily K, member 3 (KCNK3), Leu244-End, with N-terminal His tag, expressed in E.coli, 50ug


USD 249.00

In Stock*

Size
    • 50 ug

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Specifications

Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
A DNA sequence encoding the region(Leu244-End) of KCNK3
Tag N-His
Predicted MW 16.1 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 50 mM Tris-HCl, pH 8.0, 8 M urea
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_002237
Locus ID 3777
UniProt ID O14649
Cytogenetics 2p23.3
Refseq Size 2590
Refseq ORF 1182
Synonyms K2p3.1; OAT1; PPH4; TASK; TASK-1; TASK1; TBAK1
Summary This gene encodes a member of the superfamily of potassium channel proteins that contain two pore-forming P domains. The encoded protein is an outwardly rectifying channel that is sensitive to changes in extracellular pH and is inhibited by extracellular acidification. Also referred to as an acid-sensitive potassium channel, it is activated by the anesthetics halothane and isoflurane. Although three transcripts are detected in northern blots, there is currently no sequence available to confirm transcript variants for this gene. [provided by RefSeq, Aug 2008]
Protein Families Druggable Genome, Ion Channels: Potassium, Transmembrane

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