HIF 2 alpha (EPAS1) (NM_001430) Human Recombinant Protein

CAT#: TP762188

Purified recombinant protein of Human endothelial PAS domain protein 1 (EPAS1), Leu584-end, with N-terminal His tag, expressed in E.coli, 50ug

Product Images

Purified recombinant protein EPAS1 was analyzed by SDS-PAGE gel and Coomossie Blue Staining.

Specifications

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  A DNA sequence encoding the region(Leu584-end) of EPAS1
• Tag: N-His
• Predicted MW: 31.1 kDa
• Concentration: >0.05 µg/µL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 50 mM Tris-HCl, pH 8.0, 8 M urea
• Note: For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
• Storage: Store at -80°C.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_001421
• Locus ID: 2034
• UniProt ID: Q99814, B3KW07
• Cytogenetics: 2p21
• Refseq Size: 5184
• Refseq ORF: 2610
• Synonyms: bHLHe73; ECYT4; HIF2A; HLF; MOP2; PASD2
• Summary: This gene encodes a transcription factor involved in the induction of genes regulated by oxygen, which is induced as oxygen levels fall. The encoded protein contains a basic-helix-loop-helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels. Mutations in this gene are associated with erythrocytosis familial type 4. [provided by RefSeq, Nov 2009]
• Protein Families: Druggable Genome, Transcription Factors
• Protein Pathways: Pathways in cancer, Renal cell carcinoma