Folate Receptor 4 (IZUMO1R) (NM_001080486) Human Recombinant Protein

CAT#: TP761039

Purified recombinant protein of Human folate receptor 4 (delta) homolog (mouse) (FOLR4), full length, with N-terminal HIS tag, expressed in E.coli, 50ug

Product Images

Specifications

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  A DNA sequence encoding human full-length FOLR4
• Tag: N-His
• Predicted MW: 27.8 kDa
• Concentration: >0.05 µg/µL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 25 mM Tris-HCl, pH 8.0, 150 mM NaCl, 1% sarkosyl, 10% glycerol
• Note: For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
• Storage: Store at -80°C.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_001073955
• Locus ID: 390243
• UniProt ID: A6ND01
• Cytogenetics: 11q21
• Refseq Size: 732
• Refseq ORF: 729
• Synonyms: folate receptor 4 (delta) homolog; folate receptor 4 (delta) homolog (mouse); Folbp3
• Summary: Receptor for IZUMO1 present at the cell surface of oocytes (oolemma), which is essential for species-specific gamete recognition and fertilization. The IZUMO1:IZUMO1R/JUNO interaction is a necessary adhesion event between sperm and egg that is required for fertilization but is not sufficient for cell fusion. The ligand-receptor interaction probably does not act as a membrane 'fusogen'. Does not bind folate.[UniProtKB/Swiss-Prot Function]