BTN3A1 Human Recombinant Protein

CAT#: TP728060

Biotinylated Human BTN3A1 (C-Fc-Avi)

Specifications

Product Data

• Species: Human
• Protein Source: Human
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  Gln30-Gly254
• Tag: C-Fc-Avi
• Buffer: Lyophilized from a 0.2 um filtered solution of PBS, pH7.4.
• Note: Biotinylated Recombinant Human Butyrophilin Subfamily 3 Member A1 is produced by our Mammalian expression system and the target gene encoding Gln30-Gly254 is expressed with a Fc, Avi tag at the C-terminus.
• Stability: 12 months from date of despatch

Reference Data

• Locus ID: 11119
• UniProt ID: O00481
• Summary: Butyrophilin Subfamily 3 Member A1 (BTN3A1/CD277) is a type I transmembrane glycoprotein member of the Ig superfamily. It is expressed on a wide variety of immune cells. Similar to BTN3A2 and BTN3A3, BTN3A1 is composed of an extracellular N-terminal IgV and a membraneproximal IgC domain followed by a transmembrane domain and a cytoplasmic tail. These Ig domains are also found in B7 family costimulatory molecules, suggesting structural and functional similarities between the two protein families. BTN3A1 acts as a critical protein for the activation of Vγ9Vδ2 T cells following detection of distressed cells. The anti-tumor responses of Vγ9Vδ2 T cells may be enhanced with agonistic anti-BTNA3 antibodies.