Saccharomyces cerevisiae Recombinant Protein

CAT#: TP727593

Recombinant S. cerevisiae TIM16

Specifications

Product Data

• Species: Saccharomyces cerevisiae
• Protein Source: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  Thr54-Ala119
• Buffer: Lyophilized from a 0.2 um filtered solution of 20mM Tris-HCl, 300mM NaCl, pH 8.0 .
• Note: Recombinant S. cerevisiae Mitochondrial Import Inner Membrane Translocase Subunit TIM16 is produced by our E.coli expression system and the target gene encoding Thr54-Ala119 is expressed.
• Stability: 12 months from date of despatch

Reference Data

• Summary: Mitochondrial import inner membrane translocase subunit TIM16 (TIM16) is an ssential component of the PAM complex. PAM complex is required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. In the complex, TIM16 is required to regulate activity of mtHSP70 (SSC1) via its interaction with PAM18/TIM14. TIM16 may act by positioning PAM18/TIM14 in juxtaposition to mtHSP70 at the translocon to maximize ATPase stimulation.