Pdgfa Mouse Recombinant Protein

CAT#: TP724802

Recombinant Mouse PDGF-A (N-FLAG)

Specifications

Product Data

• Species: Mouse
• Protein Source: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  S87-T211
• Tag: N-FLAG
• Buffer: Supplied as a 0.2 um filtered solution of PBS, um Urea pH 7.4
• Note: Recombinant Mouse PDGF-A is produced by E.coli. The target gene encoding S87-T211 is expressed with a FLAG tag at the N-terminus.
• Stability: 12 months from date of despatch

Reference Data

• Locus ID: 18590
• UniProt ID: P20033
• Summary: Platelet-derived growth factor alpha (PDGFA) is a member of PDGF family. PDGFA can form disulfide-linked homodimer or heterodimer with PDGFB. PDGF proteins mediate diverse cellular functions by binding to and inducing the homo- or hetero-dimerization of two receptors (PDGF R alpha and R beta). PDGFA is expressed in multiple cell types, tissues and is upregulated in various cancers. It is proposed that PDGFA can play a key role in the development and progression of tumor growth by regulating cell proliferation, angiogenesis and metastasis.