Ifng Mouse Recombinant Protein
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Specifications
Product Data | |
Species | Mouse |
Protein Source | Expi293 |
Expression cDNA Clone or AA Sequence |
His23-Cys155
|
Buffer | Lyophilized from a 0.2 um filtered solution of PBS, pH7.4 |
Note | Recombinant Mouse Interferon Gamma is produced by our Mammalian expression system and the target gene encoding His23-Cys155 is expressed. |
Stability | 12 months from date of despatch |
Reference Data | |
Locus ID | 15978 |
UniProt ID | P01580 |
Summary | Mouse Interferon-gamma (IFN-γ/IFNG) is a secreted protein that belongs to the type II (gamma) interferon family. IFNG is primarily expressed by T lymphocytes, and activated by specific antigens or mitogens. In addition to having antiviral activity, IFNG also has important immunoregulatory functions. It is a potent activator of macrophages and has antiproliferative effects on transformed cells as well as enhance the antitumor effects of the type I interferons. IFNG also functions as an anti-inflammatory mediator by promoting the development of regulatory T cells and inhibiting Th17 cell differentiation. The pleiotropic effects of IFN-gamma contribute to the development of multiple aspects of atherosclerosis. |
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