B7H3 (CD276) Human Recombinant Protein

CAT#: TP724676

Recombinant Human B7H3-4Ig/B7-H3b (C-mFc)

Specifications

Product Data

• Species: Human
• Protein Source: Human
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  Gly27-Thr461
• Tag: C-Mouse Fc
• Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
• Note: Recombinant Human B7H3-4Ig/B7-H3b (C-mFc) is produced by Human Cells. The target gene encoding Gly27-Thr461 is expressed with a C-mFc tag.
• Stability: 12 months from date of despatch

Reference Data

• Locus ID: 80381
• UniProt ID: Q5ZPR3
• Summary: Human B7 homolog 3 (B7-H3) is a member of the B7 family of immune proteins that provide signals for the regulation of immune responses. Other family members include B7-1, B7-2, B7-H1/PD-L1, B7-H2, and PD-L2. B7 family proteins are type I transmembrane immunoglobulin (Ig) superfamily members that contain extracellular Ig V‑like and Ig C‑like domains with a short cytoplasmic tail. Termed 4IgB7-H3 or B7-H3b, this molecule has two additional Ig-like domains (one V‑type and one C‑type) and shows a ubiquituous expression pattern.