IGFBP2 Human Recombinant Protein

CAT#: TP724639

Recombinant Human Insulin-like Growth Factor Binding Protein 2/IGFBP2 (C-hFc)

Specifications

Product Data

• Species: Human
• Protein Source: Human 293
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  A36-Q325
• Tag: C-hFc
• Buffer: Supplied as a 0.2 um filtered solution of PBS, pH7.4
• Note: Recombinant Human Insulin-like Growth Factor Binding Protein 2 is produced by Human 293 Cells. The target gene encoding A36-Q325 is expressed with a hFc tag at the C terminus.
• Stability: 12 months from date of despatch

Reference Data

• Locus ID: 3485
• UniProt ID: P18065
• Summary: Insulin-like Growth Factor Binding Protein 2 (IGFBP2) is a member of IGF binding protein superfamily. IGFBP2 is expressed in a number of tissues during development. The highest expression level is found in the central nervous system. In adults, high expression levels are also detected in the central nervous system as well as reproductive tissues. IGFBP2 prolongs the half-life of the IGFs and have been shown to either inhibit or stimulate the growth-promoting effects of the IGFs on cell culture. In addition, IGFBP2 is overexpressed in many malignancies and is often correlated with an increasingly malignant status of the tumor, indicating potential involvement of IGFBP2 in tumorigenesis.