SARS-CoV-2 (Kappa) nCoV S Protein RBD Protein, hFc Tag

CAT#: TP724171

SARS-CoV-2 (Kappa) nCoV S Protein RBD Protein, hFc Tag

Specifications

Product Data

• Expression Host: HEK293
• Tag: C-Human Fc
• Predicted MW: The protein has a predicted molecular mass of 51.2 kDa after removal of the signal peptide.The apparent molecular mass of RBD(L452R& E484Q)-hFc is approximately 55-70 kDa due to glycosylation.
• Purity: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
• Reconstitution: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization.
• Storage: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
• Stability: 12 months from date of despatch

Reference Data

• Summary: SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) also known as Covid19 (2019 Novel Coronavirus) is a virus that causes illnesses ranging from the common cold to severe diseases. The spike protein is a type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which accounts for recognizing the cell surface receptor, ACE2. S2 contains basic elements needed for the membrane fusion. Recent publications indicate that S1-RBD domain can induce virus neutralizing-antibody and T cell response.