BCMA (TNFRSF17) Human Recombinant Protein

CAT#: TP723958

Human BCMA Protein, mFc Tag

Product Images

Figure 1. Human BCMA, mFc Tag on SDS-PAGE under reducing condition.

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  Figure 2. ELISA plate pre-coated by 2 µg/ml (100 µl/well) Human BAFF, hFc tagged protein (TP723963) can bind Human BCMA, mFc tagged protein (TP723958) in a linear range of 0.03-15.625 ng/ml.

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  Figure 3. ELISA plate pre-coated by 2 µg/ml (100 µl/well) Human BCMA, mFc tagged protein (TP723958) can bind Anti-BCMA Neutralizing antibody (BME100028) in a linear range of 0.64-80.0 ng/ml.

Specifications

Product Data

• Species: Human
• Expression Host: HEK293
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  BCMA（Met1-Ala54）+mFc（Pro99-Lys330）
• Tag: C-Mouse Fc
• Predicted MW: 32.1 kDa
• Purity: > 95%
• Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5% - 8% trehalose is added as protectants before lyophilization
• Bioactivity: EC50=3.163
• Reconstitution: Reconstitute with deionized water
• Preparation: Affinity purification
• Applications: ELISA
• Storage: Store the lyophilized protein at -20°C.
  After reconstitution, store the protein at -80°C for 12 months.
  Avoid repeated freezing and thawing.
• Stability: 12 months from date of despatch

Reference Data

• Locus ID: 608
• UniProt ID: Q02223
• Summary: B-cell maturation protein (BCMA or BCM), is also known as Tumor necrosis factor receptor superfamily member 17 (TNFRSF17), which is encoded by the TNFRSF17 gene. TNFRSF17 is a cell surface receptor of the TNF receptor superfamily which recognizes B-cell activating factor (BAFF). This receptor is expressed in immune organs and mature B cell lines. BCMA promotes B-cell survival and plays a role in the regulation of humoral immunity. BCMA can activate NF-kappa-B and JNK.