IGF1 (NM_000618) Human Recombinant Protein

CAT#: TP720018

Recombinant protein of human insulin-like growth factor 1 (somatomedin C) (IGF1), transcript variant 4


 Product Datasheet for 'TP720018'

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USD 299.00


Availability*
2 Weeks

Size
    • 10 ug


Product images

Specifications

Product Data
Description Recombinant protein of human insulin-like growth factor 1 (somatomedin C) (IGF1), transcript variant 4
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence A DNA sequence from TrueORF clone, RC212527, encoding the mature peptide (Gly49-Ala118) of human IGF1 R3
Tag Tag Free
Predicted MW 9.1 kDa
Concentration Resuspend the protein to the desired concentration in proper buffer.
Purity >95% as determined by SDS-PAGE and Coomassie blue staining
Buffer Lyophilized from a 0.2 µM filtered solution of 300mM HAc-NaAc, pH 6.5.
Bioactivity ED50 is greater than 200 ng/ml as determined by an IGF binding protein assay.
Endotoxin < 0.1 EU per µg protein as determined by LAL test
Reference Data
RefSeq NP_000609
Locus ID 3479
Refseq Size 7260
Cytogenetics 12q23.2
Refseq ORF 459
Synonyms IGF-I; IGFI; MGF
Summary The protein encoded by this gene is similar to insulin in function and structure and is a member of a family of proteins involved in mediating growth and development. The encoded protein is processed from a precursor, bound by a specific receptor, and secreted. Defects in this gene are a cause of insulin-like growth factor I deficiency. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate mature protein. [provided by RefSeq, Sep 2015]
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein
Protein Pathways Dilated cardiomyopathy, Focal adhesion, Glioma, Hypertrophic cardiomyopathy (HCM), Long-term depression, Melanoma, mTOR signaling pathway, Oocyte meiosis, p53 signaling pathway, Pathways in cancer, Progesterone-mediated oocyte maturation, Prostate cancer

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Other Versions

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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