F10 (NM_007972) Mouse Recombinant Protein
Specifications
| Product Data | |
| Species | Mouse |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-MYC/DDK |
| Predicted MW | 54 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C after receiving vials. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_031998 |
| Locus ID | 14058 |
| UniProt ID | O88947 |
| Cytogenetics | 8 5.73 cM |
| RefSeq Size | 2503 |
| RefSeq ORF | 1443 |
| Synonyms | AI1947; Cf10; fX |
| Summary | This gene encodes factor X, a component of both the intrinsic and extrinsic blood coagulation pathways. The encoded protein is a zymogen that undergoes further processing in a vitamin K-dependent manner to generate mature factor X, a heterodimer comprised of disulfide-linked heavy and light chains. The mature factor X is proteolytically activated either by factor IXa (intrinsic pathway) or factor VIIa (extrinsic pathway) to form factor Xa serine endopeptidase. Activated factor Xa catalyzes the conversion of prothrombin to thrombin. A complete lack of the encoded protein is fatal to mice. A severe deficiency of the encoded protein in mice causes age-dependent iron deposition and cardiac fibrosis. Alternative splicing results in multiple transcript variants encoding different isoforms. provided by RefSeq, Aug 2015 |
| Protein Categories | Cardiovascular diseases, Enzyme: Peptidases, Secreated Proteins |
Reviews
Documents
| FAQs |
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Resources
| Recombinant Protein Resources |
Other "F10" proteins (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH308506 | F10 MS Standard C13 and N15-labeled recombinant protein (NP_000495) | 10 ug |
$3,360.00
|
|
| LC400172 | Lyophilized F10 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY400172 | Transient overexpression lysate of coagulation factor X (F10) (as WB positive control) | 100 ug |
$436.00
|
|
| TP308506 | Recombinant protein of human coagulation factor X (F10), 20 µg | 20 ug |
$867.00
|
|
Citations
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