TNFSF18 (NM_005092) Human Recombinant Protein

CAT#: TP310901L

Recombinant protein of human tumor necrosis factor (ligand) superfamily, member 18 (TNFSF18), 1 mg

Product Images

Coomassie blue staining of purified TNFSF18 protein (Cat# TP310901). The protein was produced from HEK293T cells transfected with TNFSF18 cDNA clone (Cat# RC210901) using MegaTran 2.0 (Cat# TT210002).

Specifications

Product Data

• Species: Human
• Expression Host: HEK293T
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  >RC210901 representing NM_005092
  Red=Cloning site Green=Tags(s)
  
  MCLSHLENMPLSHSRTQGAQRSSWKLWLFCSIVMLLFLCSFSWLIFIFLQLETAKEPCMAKFGPLPSKWQ
  MASSEPPCVNKVSDWKLEILQNGLYLIYGQVAPNANYNDVAPFEVRLYKNKDMIQTLTNKSKIQNVGGTY
  ELHVGDTIDLIFNSEHQVLKNNTYWGIILLANPQFIS
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Tag: C-Myc/DDK
• Predicted MW: 22.5 kDa
• Concentration: >0.05 µg/µL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Note: For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
• Storage: Store at -80°C.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_005083
• Locus ID: 8995
• UniProt ID: Q9UNG2, A0A0U5JXL4
• Cytogenetics: 1q25.1
• Refseq Size: 748
• Refseq ORF: 531
• Synonyms: AITRL; GITRL; hGITRL; TL6; TNLG2A
• Summary: The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF18/AITR/GITR. It has been shown to modulate T lymphocyte survival in peripheral tissues. This cytokine is also found to be expressed in endothelial cells, and is thought to be important for interaction between T lymphocytes and endothelial cells. [provided by RefSeq, Jul 2008]
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Cytokine-cytokine receptor interaction