PLA2G1B (His-tagged Fusion Protein)

CAT#: PA520X

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Total 142 AA. MW: 16 kDa (calculated). N-Terminal His-tag, 16 extra AA (highlighted).


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USD 505.00


Availability*
2 Weeks

Size
    • 100 ug


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Specifications

Product Data
Description Total 142 AA. MW: 16 kDa (calculated). N-Terminal His-tag, 16 extra AA (highlighted).
Species Human
Expression Host E. coli
Tag His-tag
Concentration 0.5 mg/ml
Purity > 95 % > 95%
Buffer 0.05M Acetate buffer pH4
Reconstitution Restore with 0.1M Acetate buffer pH4
Preparation Lyophilized (0.4 um filtered) purified protein.
Reference Data
RefSeq NP_000919
Locus ID 5319
Cytogenetics 12q24.31
Synonyms PLA2; PLA2A; PPLA2
Summary This gene encodes a secreted member of the phospholipase A2 (PLA2) class of enzymes, which is produced by the pancreatic acinar cells. The encoded calcium-dependent enzyme catalyzes the hydrolysis of the sn-2 position of membrane glycerophospholipids to release arachidonic acid (AA) and lysophospholipids. AA is subsequently converted by downstream metabolic enzymes to several bioactive lipophilic compounds (eicosanoids), including prostaglandins (PGs) and leukotrienes (LTs). The enzyme may be involved in several physiological processes including cell contraction, cell proliferation and pathological response. [provided by RefSeq, Aug 2013]
Protein Families Druggable Genome, Secreted Protein
Protein Pathways alpha-Linolenic acid metabolism, Arachidonic acid metabolism, Ether lipid metabolism, Fc epsilon RI signaling pathway, Glycerophospholipid metabolism, GnRH signaling pathway, Linoleic acid metabolism, Long-term depression, MAPK signaling pathway, Metabolic pathways, Vascular smooth muscle contraction, VEGF signaling pathway

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68 Mouse Clones