VEGFR-3 / Flt-4 (His-tagged) Human Protein

CAT#: DA3535

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VEGFR-3 / Flt-4 (His-tagged) human recombinant protein, 10 µg


Product Datasheet for 'DA3535'


USD 240.00


Availability*
2 Weeks

Size
    • 10 ug


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Specifications

Product Data
Description VEGFR-3 / Flt-4 (His-tagged) human recombinant protein, 10 µg
Species Human
Expression Host Insect
Tag His-tag
Predicted MW 120 kDa
Purity >90% by SDS-PAGE and visualised by silver stain
Buffer Presentation State: Purified
State: Lyophilized without buffer and stabilizer.
Bioactivity Biological: Measured by its ability to bind recombinant rat VEGF-C in a functional solid phase binding assay.
Immobilised recombinant human sVEGFR-3/FLT-4 at 5 µg/ml can bind recombinant rat VEGF-C in a linear range of 8-500 ng/ml.
Endotoxin < 0.1 ng per µg of sVEGFR-3
Reconstitution Restore in PBS or medium to a concentration not lower than 100 µg/ml.
Preparation Lyophilized without buffer and stabilizer.
Protein Description The recombinant mature sVEGFR-3/FLT-4 is a glycosylated monomeric protein with a mass of approximately 120 kDa. The soluble receptor protein consists of all 7 extracellular domains (Met1-Glu774).
Note Centrifuge vials before opening!
Storage Prior to and following reconstitution store the antibody at -20°C.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Reference Data
RefSeq NP_001341918
Locus ID 2324
Cytogenetics 5q35.3
Synonyms FLT-4; FLT41; LMPH1A; LMPHM1; PCL; VEGFR-3; VEGFR3
Summary This gene encodes a tyrosine kinase receptor for vascular endothelial growth factors C and D. The protein is thought to be involved in lymphangiogenesis and maintenance of the lymphatic endothelium. Mutations in this gene cause hereditary lymphedema type IA. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome, Protein Kinase, Transmembrane
Protein Pathways Cytokine-cytokine receptor interaction, Focal adhesion

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