Collagen type I (Tail Tendon) Mouse Protein

CAT#: BA143

Collagen type I (Tail Tendon) mouse protein, 0.5 mg

Specifications

Product Data

• Species: Mouse
• Concentration: lot specific
• Purity: >90% pure by SDS PAGE.
  Cross linked collagen type I dimers and trimers represent approximately 10%.
• Buffer: State: Liquid purified protein.
  Buffer System: 0.5M Acetic Acid without additives.
  Preservative: None
  Stabilizer: None
• Preparation: Liquid purified protein.
• Applications: ELISA.
• Protein Description: Preparation: Collagens were extracted from washed dissected tissue into dilute acetic acid after mild pepsin treatment. Collagen type I was purified by using differential salt precipitation. Thermal denaturation converts the collagen to gelatin.
• Note: Impurities:
  Mouse Collagen type III 10%
  Mouse collagen (other types) < 1%
  Non-collagenous proteins < 0.5%.
• Storage: Store the antigen undiluted at -20°C only.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.

Reference Data

• RefSeq: NP_031768
• Locus ID: 12842
• UniProt ID: P11087
• Cytogenetics: 11 D
• Synonyms: Co; Col; Col1; Col1a-1; Cola-1; Cola1; Mov-; Mov-13; Mov13
• Summary: This gene encodes the alpha-1 subunit of the fibril-forming type I collagen, the most abundant protein of bone, skin and tendon extracellular matrices. The encoded protein, in association with alpha-2 subunit, forms heterotrimeric type I procollagen that undergoes proteolytic processing during fibril formation. Mice lacking the encoded protein die in utero caused by the rupture of a major blood vessel. Transgenic mice expressing significantly lower levels of this gene exhibit morphological and functional defects in mineralized and non-mineralized connective tissue and, progressive loss of hearing. [provided by RefSeq, Nov 2015]