Interleukin-28B (22-196, His-tag) Human Protein

CAT#: AR51900PU-N

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Interleukin-28B (22-196, His-tag) human recombinant protein, 0.25 mg


Product Datasheet for 'AR51900PU-N'


USD 1,105.00


Availability*
2 Weeks

Size
    • 250 ug


Product images

Specifications

Product Data
Description Interleukin-28B (22-196, His-tag) human recombinant protein, 0.25 mg
Species Human
Expression cDNA Clone or AA Sequence VPVARLRGAL PDARGCHIAQ FKSLSPQELQ AFKRAKDALE ESLLLKDCKC RSRLFPRTWD LRQLQVRERP VALEAELALT LKVLEATADT DPALGDVLDQ PLHTLHHILS QLRACIQPQP TAGPRTRGRL HHWLHRLQEA PKKESPGCLE ASVTFNLFRL LTRDLNCVAS GDLCVHHHHH H
Tag His-tag
Predicted MW 20.4 kDa
Concentration 0.25 mg/ml (determined by bradford assay)
Purity >85% by SDS - PAGE
Buffer Presentation State: Purified
State: Liquid purified protein
Buffer System: Phosphate buffered saline (pH 7.4) containing 20% Glycerol, 1mM EDTA, 0.1mM PMSF
Endotoxin < 1.0 EU per 1 microgram of protein (determined by LAL method)
Preparation Liquid purified protein
Protein Description Recombinant human IFNL3, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Storage Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Reference Data
RefSeq NP_001333866
Locus ID 282617
Cytogenetics 19q13.2
Synonyms IFN-lambda-3; IFN-lambda-4; IL-28B; IL-28C; IL28B; IL28C
Summary This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28A (IL28A), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA). [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome, Secreted Protein, Transmembrane
Protein Pathways Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway

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