Myostatin (267-375, His-tag) Human Protein

CAT#: AR51737PU-S

Myostatin (267-375, His-tag) human recombinant protein, 20 µg

Product Images

Specifications

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  MGSSHHHHHH SSGLVPRGSH MGSHMDFGLD CDEHSTESRC CRYPLTVDFE AFGWDWIIAP KRYKANYCSG ECEFVFLQKY PHTHLVHQAN PRGSAGPCCT PTKMSPINML YFNGKEQIIY GKIPAMVVDR CGCS
• Tag: His-tag
• Predicted MW: 15.1 kDa
• Concentration: lot specific
• Purity: >90% by SDS - PAGE
• Presentation: Purified
• Buffer: Presentation State: Purified
  State: Liquid purified protein
  Buffer System: Liquid, In 20 mM Tris-HCl (pH 8.0) containing 10% glycerol
• Preparation: Liquid purified protein
• Protein Description: Recombinant human MSTN, fused to His-tag at N-terminus, was expressed in E.coli.
• Storage: Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer.
  Avoid repeated freezing and thawing.
  
• Stability: Shelf life: one year from despatch.

Reference Data

• RefSeq: NP_005250
• Locus ID: 2660
• UniProt ID: O14793, Q53S46
• Cytogenetics: 2q32.2
• Synonyms: GDF8; MSLHP
• Summary: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein negatively regulates skeletal muscle cell proliferation and differentiation. Mutations in this gene are associated with increased skeletal muscle mass in humans and other mammals. [provided by RefSeq, Jul 2016]
• Protein Families: Druggable Genome, Secreted Protein