Casein kinase II subunit alpha (1-391, His-tag) Human Protein

CAT#: AR50280PU-N

Casein kinase II subunit alpha (1-391, His-tag) human recombinant protein, 0.5 mg

Product Images

Specifications

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  MGSSHHHHHH SSGLVPRGSH MGSHMMSGPV PSRARVYTDV NTHRPREYWD YESHVVEWGN QDDYQLVRKL GRGKYSEVFE AINITNNEKV VVKILKPVKK KKIKREIKIL ENLRGGPNII TLADIVKDPV SRTPALVFEH VNNTDFKQLY QTLTDYDIRF YMYEILKALD YCHSMGIMHR DVKPHNVMID HEHRKLRLID WGLAEFYHPG QEYNVRVASR YFKGPELLVD YQMYDYSLDM WSLGCMLASM IFRKEPFFHG HDNYDQLVRI AKVLGTEDLY DYIDKYNIEL DPRFNDILGR HSRKRWERFV HSENQHLVSP EALDFLDKLL RYDHQSRLTA REAMEHPYFY TVVKDQARMG SSSMPGGSTP VSSANMMSGI SSVPTPSPLG PLAGSPVIAA ANPLGMPVPA AAGAQQ
• Tag: His-tag
• Predicted MW: 47.8 kDa
• Concentration: lot specific
• Purity: >90% by SDS - PAGE
• Presentation: Purified
• Buffer: Presentation State: Purified
  State: Liquid purified protein
  Buffer System: 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 0.1M NaCl, 1 mM DTT, 0.1 mM PMSF
• Preparation: Liquid purified protein
• Protein Description: Recombinant human CSNK2A1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
• Storage: Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer.
  Avoid repeated freezing and thawing.
  
• Stability: Shelf life: one year from despatch.

Reference Data

• RefSeq: NP_001886
• Locus ID: 1457
• UniProt ID: P68400
• Cytogenetics: 20p13
• Synonyms: CK2A1; Cka1; Cka2; CKII; OCNDS
• Summary: Casein kinase II is a serine/threonine protein kinase that phosphorylates acidic proteins such as casein. It is involved in various cellular processes, including cell cycle control, apoptosis, and circadian rhythm. The kinase exists as a tetramer and is composed of an alpha, an alpha-prime, and two beta subunits. The alpha subunits contain the catalytic activity while the beta subunits undergo autophosphorylation. The protein encoded by this gene represents the alpha subunit. Multiple transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Apr 2018]
• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Protein Kinase
• Protein Pathways: Adherens junction, Tight junction, Wnt signaling pathway