KLF4 (11-395, His-Cam-tag)

CAT#: AR39085PU-N

Recombinant human KLF4 protein, fused to His-CaM-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Product images

Specifications

Product Data

• Description: Recombinant human KLF4 protein, fused to His-CaM-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence: MAHHHHHHMA DQLTEEQIAE FKEAFSLFDK DGDGTITTKE LGTVMRSLGQ NPTEAELQDM INEVDADGNG TIDFPEFLTM MARKMKDTDS EEEIREAFRV FDKDGNGYIS AAELRHVMTN LGEKLTDEEV DEMIREADID GDGQVNYEEF VQMMTAKGSM AVSDALLPSF STFASGPAGR EKTLRQAGAP NNRWREELSH MKRLPPVLPG RPYDLAAATV ATDLESGGAG AACGGSNLAP LPRRETEEFN DLLDLDFILS NSLTHPPESV AATVSSSASA SSSSSPSSSG PASAPSTCSF TYPIRAGNDP GVAPGGTGGG LLYGRESAPP PTAPFNLADI NDVSPSGGFV AELLRPELDP VYIPPQQPQP PGGGLMGKFV LKASLSAPGS EYGSPSVISV SKGSPDGSHP VVVAPYNGGP PRTCPKIKQE AVSSCTHLGA GPPLSNGHRP AAHDFPLGRQ LPSRTTPTLG LEEVLSSRDC HPALPLPPGF HPHPGPNYPS FLPDQMQPQV PPLHYQELMP PGSCMPEEPK PKRGRRSWPR KRTAT
• Tag: His-Cam-tag
• Predicted MW: 58.1 kDa
• Concentration: 1.0 mg/ml (determined by Bradford assay)
• Purity: > 80 %
• Buffer: 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 1mM DTT, 0.1M NaCl
• Preparation: Liquid purified protein

Reference Data

• RefSeq: NP_001300981
• Locus ID: 9314
• Cytogenetics: 9q31.2
• Synonyms: EZF; GKLF
• Summary: This gene encodes a protein that belongs to the Kruppel family of transcription factors. The encoded zinc finger protein is required for normal development of the barrier function of skin. The encoded protein is thought to control the G1-to-S transition of the cell cycle following DNA damage by mediating the tumor suppressor gene p53. Mice lacking this gene have a normal appearance but lose weight rapidly, and die shortly after birth due to fluid evaporation resulting from compromised epidermal barrier function. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2015]
• Protein Families: Adult stem cells, Embryonic stem cells, ES Cell Differentiation/IPS, Induced pluripotent stem cells, Transcription Factors