FGF23 Mouse Protein
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Other products for "Fgf23"
Specifications
Product Data | |
Species | Mouse |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
MYPDTSPLLG SNWGSLTHLY TATARTSYHL QIHRDGHVDG TPHQTIYSAL MITSEDAGSV VITGAMTRRF LCMDLHGNIF GSLHFSPENC KFRQWTLENG YDVYLSQKHH YLVSLGRAKR IFQPGTNPPP FSQFLARRNE VPLLHFYTVR PRRHTRSAED PPERDPLNVL KPRPRATPVP VSCSRELPSA EEGGPAASDP LGVLRRGRGD ARGGAGGADR CRPFPRFV
|
Predicted MW | 25.5 kDa |
Purity | >95% pure by SDS-PAGE and HPLC analyses |
Presentation | Purified |
Buffer | Presentation State: Purified State: Lyophilized (0.2μ Sterile filtered) purified protein |
Bioactivity | Biological: Determined by its ability to stimulate the proliferation of murine NIH-3T3 cells. The expected ED50 for this effect is 0.3-0.5 μg/ml, in the presence of murine Klotho and heparin. |
Preparation | Lyophilized (0.2μ Sterile filtered) purified protein |
Protein Description | Recombinant murine FGF-23 is a 25.5 kDa globular protein containing 228 amino acid residues. |
Storage | Store lyophilized at 2-8°C for 6 months or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Reference Data | |
RefSeq | NP_073148 |
Locus ID | 64654 |
UniProt ID | Q9EPC2, Q3U1V5 |
Cytogenetics | 6 F3 |
Synonyms | Fgf8b |
Summary | This gene encodes a member of the fibroblast growth factor family. The encoded protein regulates phosphate homeostasis and vitamin D metabolism. Mutation of the related gene in humans causes autosomal dominant hypophosphatemic rickets (ADHR). The secreted protein is further cleaved into N- and C-terminal chains, which results in loss of function. [provided by RefSeq, Mar 2013] |
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