Insulin-like growth factor II / IGF2 (25-91) Human Protein

CAT#: AR09776PU-N

Insulin-like growth factor II / IGF2 (25-91) human recombinant protein, 50 µg

Product Images

Specifications

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  MAYRPSETLC GGELVDTLQF VCGDRGFYFS RPASRVSRRS RGIVEECCFR SCDLALLETY CATPAKSE
• Predicted MW: 7.6 kDa
• Concentration: lot specific
• Purity: >90%
• Presentation: Purified
• Buffer: Presentation State: Purified
  State: Liquid purified peptide
  Buffer System: PBS (pH 7.4) containing 10% glycerol
• Preparation: Liquid purified peptide
• Protein Description: Recombinant human IGF2 was expressed in E.coli and purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.
• Storage: Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.

Reference Data

• RefSeq: NP_000603
• Locus ID: 3481
• UniProt ID: P01344, C9JAF2
• Cytogenetics: 11p15.5
• Synonyms: C11orf43; GRDF; IGF-II; PP9974; SRS3
• Summary: This gene encodes a member of the insulin family of polypeptide growth factors, which are involved in development and growth. It is an imprinted gene, expressed only from the paternal allele, and epigenetic changes at this locus are associated with Wilms tumour, Beckwith-Wiedemann syndrome, rhabdomyosarcoma, and Silver-Russell syndrome. A read-through INS-IGF2 gene exists, whose 5' region overlaps the INS gene and the 3' region overlaps this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]
• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein