PTS (1-145, His-tag)

CAT#: AR09335PU-L

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Recombinant human PTS, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.


 Product Datasheet for 'AR09335PU-L'

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USD 745.00


Availability*
2 Weeks

Size
    • 500 ug


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Product Data
Description Recombinant human PTS, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Species Human
Expression Host E. coli
Tag His-tag
Concentration 1.0 mg/ml (determined by Bradford assay)
Purity > 90 % by SDS - PAGE
Buffer 20 mM Tris-HCl buffer (pH 8.0) containing 1 mM DTT, 20% glycerol
Preparation Liquid purified protein
Reference Data
RefSeq NP_000308
Locus ID 5805
Cytogenetics 11q23.1
Synonyms PTPS
Summary The enzyme encoded by this gene catalyzes the elimination of inorganic triphosphate from dihydroneopterin triphosphate, which is the second and irreversible step in the biosynthesis of tetrahydrobiopterin from GTP. Tetrahydrobiopterin, also known as BH(4), is an essential cofactor and regulator of various enzyme activities, including enzymes involved in serotonin biosynthesis and NO synthase activity. Mutations in this gene result in hyperphenylalaninemia. [provided by RefSeq, Oct 2008]
Protein Families Druggable Genome
Protein Pathways Folate biosynthesis, Metabolic pathways

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68 Mouse Clones