RANTES / CCL5 (24-91)

CAT#: AR09257PU-L

Reviews ()
Write a review

Recombinant RANTES protein was expressed in E.coli and purified by using conventional chromatography techniques.


 Product Datasheet for 'AR09257PU-L'

  View other "CCL5" proteins (9)

USD 1,570.00


Availability*
2 Weeks

Size
    • 500 ug


Product images

Specifications

Product Data
Description Recombinant RANTES protein was expressed in E.coli and purified by using conventional chromatography techniques.
Species Human
Expression Host E. coli
Concentration 0.5 mg/ml (determined by Bradford assay)
Purity > 95 % by SDS - PAGE
Buffer 10 mM Sodium Citrate (pH 3.5) containing 10% Glycerol
Endotoxin < 1.0 EU per 1 µg of protein (determined by LAL method)
Preparation Liquid purified peptide
Reference Data
RefSeq NP_001265665
Locus ID 6352
Cytogenetics 17q12
Synonyms D17S136E; eoCP; RANTES; SCYA5; SIS-delta; SISd; TCP228
Summary This gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, functions as a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells. It functions as one of the natural ligands for the chemokine receptor chemokine (C-C motif) receptor 5 (CCR5), and it suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor. Alternative splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Jul 2013]
Protein Families Druggable Genome, Secreted Protein, Transmembrane
Protein Pathways Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Epithelial cell signaling in Helicobacter pylori infection, NOD-like receptor signaling pathway, Prion diseases, Toll-like receptor signaling pathway

Documents

Other Versions

Other products for "CCL5"
Customer Reviews 
Loading...
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
68 Mouse Clones