14-3-3 protein epsilon (1-255)

CAT#: AR09100PU-N

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Recombinant human 14-3-3 e was expressed in E.coli and purified by using conventional chromatography techniques.


 Product Datasheet for 'AR09100PU-N'

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USD 400.00


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2 Weeks

Size
    • 100 ug


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Product Data
Description Recombinant human 14-3-3 e was expressed in E.coli and purified by using conventional chromatography techniques.
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence MDDREDLVYQ AKLAEQAERY DEMVESMKKV AGMDVELTVE ERNLLSVAYK NVIGARRASW RIISSIEQKE ENKGGEDKLK MIREYRQMVE TELKLICCDI LDVLDKHLIP AANTGESKVF YYKMKGDYHR YLAEFATGND RKEAAENSLV AYKAASDIAM TELPPTHPIR LGLALNFSVF YYEILNSPDR ACRLAKAAFD DAIAELDTLS EESYKDSTLI MQLLRDNLTL WTSDMQGDGE EQNKEALQDV EDENQ
Tag Tag Free
Predicted MW kDa
Concentration 1.0 mg/ml
Purity = 95 by SDS-PAGE
Buffer 20 mM Tris pH 7.5
Preparation Liquid purified protein
Reference Data
RefSeq NP_006752
Locus ID 7531
Cytogenetics 17p13.3
Synonyms 14-3-3E; HEL2; KCIP-1; MDCR; MDS
Summary This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the mouse ortholog. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. Two transcript variants, one protein-coding and the other non-protein-coding, have been found for this gene. [provided by RefSeq, Aug 2008]
Protein Families Druggable Genome
Protein Pathways Cell cycle, Neurotrophin signaling pathway, Oocyte meiosis

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BOGO Free lysates
68 Mouse Clones