Apolipoprotein A I / APO AI

USD 1,930.00


Availability*
5 Days

Size
    • 0.1 mg


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Specifications

Product Data
Description Purified Hamster Apolipoprotein AI
Species Human
Expression Host Other
Concentration 1,0 mg/ml
Purity Syrian hamster plasma, high density lipoproteins
Buffer 0.05M Tris, pH 7.4 containing 0.05% Thimerosal
Preparation Liquid purified
Reference Data
RefSeq NP_000030
Locus ID 335
Cytogenetics 11q23.3
Synonyms apo(a)
Summary This gene encodes apolipoprotein A-I, which is the major protein component of high density lipoprotein (HDL) in plasma. The encoded preproprotein is proteolytically processed to generate the mature protein, which promotes cholesterol efflux from tissues to the liver for excretion, and is a cofactor for lecithin cholesterolacyltransferase (LCAT), an enzyme responsible for the formation of most plasma cholesteryl esters. This gene is closely linked with two other apolipoprotein genes on chromosome 11. Defects in this gene are associated with HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein. [provided by RefSeq, Dec 2015]
Protein Families Druggable Genome, Secreted Protein
Protein Pathways PPAR signaling pathway

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68 Mouse Clones