Apolipoprotein A I / APO AI Hamster Protein

CAT#: AR00018PU-N

Apolipoprotein A I / APO AI hamster protein, 0.1 mg

Specifications

Product Data

• Species: Hamster
• Protein Source: Plasma
• Concentration: lot specific
• Purity: Syrian hamster plasma, high density lipoproteins
• Presentation: Purified
• Buffer: Presentation State: Purified
  State: Liquid purified
  Buffer System: 0.05M Tris, pH 7.4 containing 0.05% Thimerosal
• Preparation: Liquid purified
• Protein Description: Purified Hamster Apolipoprotein AI
• Storage: Store the protein at -70°C.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.

Reference Data

• RefSeq: NP_000030
• Locus ID: 335
• Cytogenetics: 11q23.3
• Synonyms: apo(a); HPALP2
• Summary: This gene encodes apolipoprotein A-I, which is the major protein component of high density lipoprotein (HDL) in plasma. The encoded preproprotein is proteolytically processed to generate the mature protein, which promotes cholesterol efflux from tissues to the liver for excretion, and is a cofactor for lecithin cholesterolacyltransferase (LCAT), an enzyme responsible for the formation of most plasma cholesteryl esters. This gene is closely linked with two other apolipoprotein genes on chromosome 11. Defects in this gene are associated with HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein. [provided by RefSeq, Dec 2015]
• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: PPAR signaling pathway