JAML (NM_001098526) Human Mass Spec Standard

CAT#: PH318818

AMICA1 MS Standard C13 and N15-labeled recombinant protein (NP_001091996)

  View other "JAML" proteins (5)

USD 3,255.00

3 Weeks*

    • 10 ug

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Frequently bought together (2)
Rabbit Polyclonal Anti-AMICA1 Antibody
    • 100 ul

USD 539.00

Transient overexpression lysate of adhesion molecule, interacts with CXADR antigen 1 (AMICA1), transcript variant 2
    • 100 ug

USD 436.00

Other products for "JAML"


Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC218818
Predicted MW 44.2 kDa
Protein Sequence
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Reference Data
RefSeq NP_001091996
RefSeq Size 1957
RefSeq ORF 1182
Synonyms AMICA; AMICA1; CREA7-1; CREA7-4; Gm638
Locus ID 120425
UniProt ID Q86YT9, B3KUI3
Cytogenetics 11q23.3
Summary Transmembrane protein of the plasma membrane of leukocytes that control their migration and activation through interaction with CXADR, a plasma membrane receptor found on adjacent epithelial and endothelial cells. The interaction between both receptors mediates the activation of gamma-delta T-cells, a subpopulation of T-cells residing in epithelia and involved in tissue homeostasis and repair. Upon epithelial CXADR-binding, JAML induces downstream cell signaling events in gamma-delta T-cells through PI3-kinase and MAP kinases. It results in proliferation and production of cytokines and growth factors by T-cells that in turn stimulate epithelial tissues repair. It also controls the transmigration of leukocytes within epithelial and endothelial tissues through adhesive interactions with epithelial and endothelial CXADR.[UniProtKB/Swiss-Prot Function]
Protein Families Transmembrane


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