Kv beta 1(KCNAB1) (NM_172159) Human Mass Spec Standard

CAT#: PH307384

KCNAB1 MS Standard C13 and N15-labeled recombinant protein (NP_751891)

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USD 1,995


Availability*
3 Weeks

Size
    • 10 ug

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Specifications

Product Data
Description KCNAB1 MS Standard C13 and N15-labeled recombinant protein (NP_751891)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC207384
Predicted MW 44.5 kDa
Protein Sequence
Tag C-MYC/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration 50 ug/ml as determined by BCA
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 100 mM glycine, 25 mM Tris-HCl, pH 7.3. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.
Reference Data
RefSeq NP_751891
RefSeq Size 4094
RefSeq ORF 1203
Synonyms AKR6A3; hKvb3; hKvBeta3; KCNA1B; KV-BETA-1; Kvb1.3
Locus ID 7881
Cytogenetics 3q25.31
Summary Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member includes distinct isoforms which are encoded by alternatively spliced transcript variants of this gene. Some of these isoforms are beta subunits, which form heteromultimeric complexes with alpha subunits and modulate the activity of the pore-forming alpha subunits. [provided by RefSeq, Apr 2015].
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