FGF 23 (FGF23) Rabbit Monoclonal Antibody [Clone ID: OTIR5D11]

CAT#: TA592951

FGF23 Rabbit monoclonal antibody,clone OTIR5D11

Product Images

Figure A, Western blot analysis of overexpressed lysates(15ug per lane) from HEK293T cells transfected with empty plasmid (PS100001, lane 1) , human FGF23 plasmid (RC210127, lane 2), mouse FGF23 plasmid (MR227482, lane 3) using anti-FGF23 antibody TA592951 (1:5000). Figure B, Western blot analysis of the same samples as figure A with anti-DDK antibody (TA180144, 1:1000)

Specifications

Product Data

• Clone Name: OTIR5D11
• Applications: WB
• Recommended Dilution: WB 1:1000-1:5000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Monoclonal
• Immunogen: Full length human recombinant protein of human FGF23 (NP_065689) produced in E.coli.
• Formulation: PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Storage: Shipped at -20°C or with ice packs, Upon delivery store at -20°C. Dilute in PBS(pH7.3) if necessary. Stable for 12 months from date of receipt. Avoid repeated freeze-thaws.
• Predicted Protein Size: 28 kDa
• Gene Name: fibroblast growth factor 23
• Database Link:
  NP_065689
  Entrez Gene 8074 Human
  UniProt ID Q9GZV9
• Background: This gene encodes a member of the fibroblast growth factor family of proteins, which possess broad mitogenic and cell survival activities and are involved in a variety of biological processes. The product of this gene regulates phosphate homeostasis and transport in the kidney. The full-length, functional protein may be deactivated via cleavage into N-terminal and C-terminal chains. Mutation of this cleavage site causes autosomal dominant hypophosphatemic rickets (ADHR). Mutations in this gene are also associated with hyperphosphatemic familial tumoral calcinosis (HFTC). [provided by RefSeq, Feb 2013]
• Synonyms: ADHR; FGFN; HFTC2; HPDR2; HYPF; PHPTC

Reference Data

• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: MAPK signaling pathway, Melanoma, Pathways in cancer, Regulation of actin cytoskeleton