TNFAIP1 Rabbit Polyclonal Antibody

CAT#: TA392799

TNF-IP 1 (S122) polyclonal antibody

Product Images

Western blot (WB) analysis of TNF-IP 1 (S122) pAb at 1:500 dilution Lane1:A549 whole cell lysate(40ug) Lane2:Hela whole cell lysate(40ug) Lane3:PC12 whole cell lysate(40ug) Lane4:3T3-L1 whole cell lysate(40ug) Lane5:BV2 whole cell lysate(40ug)

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  Immunohistochemistry (IHC) analyzes of TNF-IP 1 (S122) pAb in paraffin-embedded human colorectal carcinoma tissue at 1:50.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500~1:1000 IHC: 1:50~1:200
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide, corresponding to amino acids 90-140 of Human TNF-IP 1.
• Specificity: TNF-IP 1 (S122) polyclonal antibody detects endogenous levels of TNF-IP 1 protein.
• Formulation: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
• Concentration: 1mg/ml
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
• Stability: 1 year
• Predicted Protein Size: ~ 36 kDa
• Gene Name: TNF alpha induced protein 1
• Database Link:
  Entrez Gene 7126 Human
  UniProt ID Q13829
• Background: TNFα-IP 1 (tumor necrosis factor, α-induced protein 1, endothelial), also known as B12, B61, EDP1 or TNFAIP1, is a BTB/POZ domain-containing protein that belongs to the KCTD10/KCTD13/TNFAIP1 family. TNFα-IP 1 contains one BTB/POZ motif, which is known to mediate homomeric and heteromeric POZ-POZ interactions and is common to transcriptional regulators involved in chromatin modeling. The expression of TNFα-IP 1 can be induced by IL-6 and by TNFα in the umbilical vein of endothelial cells. TNFα-IP 1 may be involved in DNA repair, DNA synthesis, cell apoptosis and human diseases. TNFα-IP 1 is suggested to play a role in the process of cancer and in the innate immunity against the Hepatitis B virus.
• Synonyms: BACURD2; BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2; BTB/POZ domain-containing protein TNFAIP1; EDP1; hBACURD2; Protein B12; TNFAIP1; Tumor necrosis factor, alpha-induced protein 1, endothelial
• Note: For research use only, not for use in diagnostic procedure.