Parp1 Rabbit Polyclonal Antibody

CAT#: TA389680

Cleaved PARP (Asp214) Rabbit pAb

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB,1:1000 - 1:2000
• Reactivities: Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Formulation: PBS with 0.05% proclin300,50% glycerol,pH7.3.
• Concentration: lot specific
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: poly (ADP-ribose) polymerase family, member 1
• Database Link:
  Entrez Gene 11545 Mouse
  UniProt ID Q921K2
• Background: This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.
• Synonyms: ADPRT; ADPRT1; pADPRT-1; PARP; PARP-1; poly(ADP-ribosyl)transferase; PPOL