Anti-IL5 antibody(DMC274), IgG1 Chimeric mAb

CAT#: TA389494

Anti-IL5 antibody(DMC274), IgG1 Chimeric mAb

Specifications

Product Data

• Applications: FC
• Recommended Dilution: Flow Cyt 1:100
• Reactivities: Human
• Host: Rabbit
• Clonality: Monoclonal
• Formulation: 1XPBS
• Concentration: Lot specific
• Purification: Purified from cell culture supernatant by affinity chromatography
• Conjugation: Unconjugated
• Storage: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature.
• Stability: 12 months from date of despatch
• Background: This gene encodes a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. The encoded cytokine plays a major role in the regulation of eosinophil formation, maturation, recruitment and survival. The increased production of this cytokine may be related to pathogenesis of eosinophil-dependent inflammatory diseases. This cytokine functions by binding to its receptor, which is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). This gene is located on chromosome 5 within a cytokine gene cluster which includes interleukin 4 (IL4), interleukin 13 (IL13), and CSF2 . This gene, IL4, and IL13 may be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31.
• Synonyms: IL-5,TRF,Interleukin-5,EDF