Anti-VEGFR2 antibody(DM185), Rabbit mAb

CAT#: TA389400

Anti-VEGFR2 antibody(DM185), Rabbit mAb

Specifications

Product Data

• Clone Name: DM185
• Applications: ELISA, FC
• Recommended Dilution: ELISA 1:5000-10000
  Flow Cyt 1:100
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Monoclonal
• Formulation: 1XPBS
• Concentration: Lot specific
• Purification: Purified from cell culture supernatant by affinity chromatography
• Conjugation: Unconjugated
• Storage: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature.
• Stability: 12 months from date of despatch
• Background: Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas.
• Synonyms: CD309, FLK1, VEGFR, VEGFR2