Pdcd1lg2 Rabbit Monoclonal Antibody [Clone ID: TY25]

CAT#: TA386142

Recombinant Anti-PD-L2 (Clone TY25)

Specifications

Product Data

• Clone Name: TY25
• Applications: Bl, FC, IP, WB
• Reactivities: Mouse
• Host: Rabbit
• Isotype: IgG, kappa
• Clonality: Monoclonal
• Immunogen: This antibody was raised by immunising SD rats with B7-DC-transfected RAW264.7 cells and selected on B7-DC-transfected NRK.
• Specificity: This antibody binds to mouse PD-L2 and competes with PD-1 binding. It does not cross-react with PD-L1.
  
  This antibody has been used to detect murine PD-L2 by flow cytometry on stimulated dendritic cells as well as various mouse tumour cells. It also detects immunoprecipitates mouse PD-L2 and can be used to detect it by non-reducing Western Blot. TY25 inhibits PD-L2 binding to PD-1 transfected cells (Ansari et al. 2003, PMID: 12847137) and thereby blocks PD-L2 : PD-1 signalling.
• Formulation: PBS with 0.02% Proclin 300.
• Concentration: lot specific
• Conjugation: Unconjugated
• Storage: Please store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C. Avoid freeze and thaw cycles.
• Stability: 3 years from dispatch.
• Gene Name: programmed cell death 1 ligand 2
• Database Link:
  Entrez Gene 58205 Mouse
  UniProt ID Q9WUL5
• Synonyms: B7-DC; B7DC; bA574F11.2; Btdc; CD273; MGC142238; MGC142240; PD-L2; PDCD1L2; PDL2
• Note: This chimeric rabbit antibody was made using the variable domain sequences of the original Rat IgG2a format, for improved compatibility with existing reagents, assays and techniques.