RAC3 Rabbit Monoclonal Antibody [Clone ID: R01-6I8]

CAT#: TA385115

Rac3 Rabbit monoclonal Antibody

Product Images

Western blot analysis of RAC3 in K562, rat Brain lysates using Rac3 antibody.

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  Immunohistochemistry analysis of paraffin-embedded Human breast cancer using RAC3 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Specifications

Product Data

• Clone Name: R01-6I8
• Applications: IHC, WB
• Recommended Dilution: WB: 1/1000
  IHC: 1/20
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Monoclonal
• Immunogen: A synthetic peptide of human RAC3
• Formulation: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: Calculated MW: 21 kDa; Observed MW: 21 kDa
• Gene Name: ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
• Database Link:
  Entrez Gene 5881 Human
  UniProt ID P60763
• Background: Swiss-Prot Acc.P60763.Plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses, such as cell spreading and the formation of actin-based protusions including lamellipodia and membrane ruffles. Promotes cell adhesion and spreading on fibrinogen in a CIB1 and alpha-IIb/beta3 integrin-mediated manner.
• Synonyms: p21-Rac3