NUF2 Rabbit Monoclonal Antibody [Clone ID: R07-9E2]

CAT#: TA384904

Nuf2 Rabbit monoclonal Antibody

Product Images

Western blot analysis of Nuf2 in K562 lysates using Nuf2 antibody.

Specifications

Product Data

• Clone Name: R07-9E2
• Applications: WB
• Recommended Dilution: WB: 1/1000-1/5000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Monoclonal
• Immunogen: A synthetic peptide of human Nuf2
• Formulation: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: Calculated MW: 54 kDa; Observed MW: 54 kDa
• Database Link:
  UniProt ID Q9BZD4
• Background: Swiss-Prot Acc.Q9BZD4.Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity (PubMed:12438418, PubMed:14654001, PubMed:15062103, PubMed:15235793, PubMed:15239953, PubMed:15548592, PubMed:17535814). Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore (PubMed:15548592). The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules (PubMed:23085020).