MAP2K1 Rabbit Polyclonal Antibody

CAT#: TA384703

Phospho-MEK1 (Ser298) Rabbit polyclonal Antibody

Product Images

Western blot analysis of Phospho-MEK1 (S298) in (1) HeLa treated with LP lysates; (2) HeLa lysates using Phospho-MEK1 (Ser298) antibody.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1/1000-1/2000
  IHC: 1/50-1/200
  ICC/IF: 1/50-1/200
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: A synthesized peptide derived from human MEK1 (Phosphorylated)
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: lot specific
• Purification: Affinity Chromatography
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: 45kDa
• Database Link:
  UniProt ID Q02750
• Background: Swiss-Prot Acc.Q02750.Activation of MEK1 and MEK2 occurs through phosphorylation of two serine residues at positions 217 and 221, located in the activation loop of subdomain VIII, by Raf-like molecules. Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. Activates ERK1 and ERK2 MAP kinases.