LRP1 Rabbit Polyclonal Antibody

CAT#: TA384676

LRP1 Rabbit polyclonal Antibody

Product Images

Western blot analysis of LRP1 in U87-MG and Hela lysates using LRP1 antibody.

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  Immunohistochemistry analysis of paraffin-embedded Human liver carcinoma using LRP1 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Specifications

Product Data

• Applications: FC, IF, IHC, IP, WB
• Recommended Dilution: WB: 1/10000-1/20000
  IHC: 1/50-1/100
  ICC/IF: 1/50-1/100
  IP: 1/30
  FC: 1/50
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: A synthesized peptide derived from human LRP1
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: lot specific
• Purification: Affinity Chromatography
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: 85kDa
• Gene Name: LDL receptor related protein 1
• Database Link:
  Entrez Gene 4035 Human
  UniProt ID Q07954
• Background: Swiss-Prot Acc.Q07954.Endocytic receptor involved in endocytosis and in phagocytosis of apoptotic cells. Required for early embryonic development. Involved in cellular lipid homeostasis. Involved in the plasma clearance of chylomicron remnants and activated LRPAP1 (alpha 2-macroglobulin), as well as the local metabolism of complexes between plasminogen activators and their endogenous inhibitors. May modulate cellular events, such as APP metabolism, kinase-dependent intracellular signaling, neuronal calcium signaling as well as neurotransmission.Functions as a receptor for Pseudomonas aeruginosa exotoxin A.
• Synonyms: A2MR; APOER; APR; CD91; FLJ16451; IGFBP3R; LRP; MGC88725; TGFBR5