HRH3 Rabbit Monoclonal Antibody [Clone ID: R04-3I4]

CAT#: TA384453

HRH3 Rabbit monoclonal Antibody

Product Images

Western blot analysis of HRH3/Histamine 3 Receptor in K562, C6, 3T3 lysates using HRH3 antibody.

Specifications

Product Data

• Clone Name: R04-3I4
• Applications: WB
• Recommended Dilution: WB: 1/1000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Monoclonal
• Immunogen: A synthetic peptide of human HRH3/Histamine 3 Receptor
• Formulation: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: Calculated MW: 49 kDa; Observed MW: 49 kDa
• Gene Name: histamine receptor H3
• Database Link:
  Entrez Gene 11255 Human
  UniProt ID Q9Y5N1
• Background: Swiss-Prot Acc.Q9Y5N1.The H3 subclass of histamine receptors could mediate the histamine signals in CNS and peripheral nervous system. Signals through the inhibition of adenylate cyclase and displays high constitutive activity (spontaneous activity in the absence of agonist). Agonist stimulation of isoform 3 neither modified adenylate cyclase activity nor induced intracellular calcium mobilization.MiscellaneousDoes not bind to cimetidine and tripolidine. Shows modest affinity for thioperamide, imetit, N-alpha-methylhistamine and R--alpha-methylhistamine. Isoform 4 is unable to bind to iodoproxyfan while isoforms 1 and 3 bind it with high affinity.
• Synonyms: GPCR97; HH3R