HRH3 Rabbit Monoclonal Antibody [Clone ID: R04-3I4]

CAT#: TA384453

HRH3 Rabbit monoclonal Antibody

USD 380.00

4 Weeks*

    • 100 ul

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Product Data
Clone Name R04-3I4
Applications WB
Recommended Dilution WB: 1/1000
Reactivities Human, Mouse, Rat
Host Rabbit
Isotype IgG
Clonality Monoclonal
Immunogen A synthetic peptide of human HRH3/Histamine 3 Receptor
Formulation 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Concentration lot specific
Purification Affinity Purified
Conjugation Unconjugated
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Stability 1 year
Predicted Protein Size Calculated MW: 49 kDa; Observed MW: 49 kDa
Gene Name histamine receptor H3
Background Swiss-Prot Acc.Q9Y5N1.The H3 subclass of histamine receptors could mediate the histamine signals in CNS and peripheral nervous system. Signals through the inhibition of adenylate cyclase and displays high constitutive activity (spontaneous activity in the absence of agonist). Agonist stimulation of isoform 3 neither modified adenylate cyclase activity nor induced intracellular calcium mobilization.MiscellaneousDoes not bind to cimetidine and tripolidine. Shows modest affinity for thioperamide, imetit, N-alpha-methylhistamine and R--alpha-methylhistamine. Isoform 4 is unable to bind to iodoproxyfan while isoforms 1 and 3 bind it with high affinity.
Synonyms GPCR97; HH3R
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.