HB EGF (HBEGF) Rabbit Monoclonal Antibody [Clone ID: R08-9C2]

CAT#: TA384400

HBEGF Rabbit monoclonal Antibody

Product Images

Western blot analysis of HBEGF in K562, C6, 3T3, Hela lysates using HBEGF antibody.

Specifications

Product Data

• Clone Name: R08-9C2
• Applications: WB
• Recommended Dilution: WB: 1/2000-1/10000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Monoclonal
• Immunogen: A synthetic peptide of human HBEGF
• Formulation: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: Calculated MW: 23 kDa; Observed MW: 23 kDa
• Gene Name: heparin binding EGF like growth factor
• Database Link:
  Entrez Gene 1839 Human
  UniProt ID Q99075
• Background: Swiss-Prot Acc.Q99075.Growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor.SitesFeature keyPosition(s)Description
• Synonyms: DTR; DTS; DTSF; HEGFL