Cytochrome P450 17A1 (CYP17A1) Rabbit Monoclonal Antibody [Clone ID: R08-2J5]

CAT#: TA384079

Cytochrome P450 17A1 Rabbit monoclonal Antibody

Product Images

Western blot detection of Cytochrome P450 17A1/CYP17A1 in K562,C6,3T3 cell lysates using Cytochrome P450 17A1/CYP17A1 Rabbit mAb(1:1000 diluted).Predicted band size:57kDa.Observed band size:55kDa.

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  Immunohistochemistry analysis of paraffin-embedded mouse kidney using Cytochrome P450 17A1 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

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  Immunocytochemistry of Cytochrome P450 17A1(green) in Hela cells using Cytochrome P450 17A1 Rabbit mAb at dilution 1/50, and DAPI(blue)

Specifications

Product Data

• Clone Name: R08-2J5
• Applications: IF, IHC, IP, WB
• Recommended Dilution: WB: 1/1000-1/5000
  IHC: 1/20
  ICC/IF: 1/20
  IP: 1/20
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Monoclonal
• Immunogen: A synthetic peptide of human Cytochrome P450 17A1
• Formulation: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: Calculated MW: 57 kDa; Observed MW: 55 kDa
• Gene Name: cytochrome P450 family 17 subfamily A member 1
• Database Link:
  Entrez Gene 1586 Human
  UniProt ID P05093
• Background: Swiss-Prot Acc.P05093.Conversion of pregnenolone and progesterone to their 17-alpha-hydroxylated products and subsequently to dehydroepiandrosterone (DHEA) and androstenedione. Catalyzes both the 17-alpha-hydroxylation and the 17,20-lyase reaction. Involved in sexual development during fetal life and at puberty.
• Synonyms: CPT7; CYP17; CYPXVII; P450-C17; P450C17; S17AH