Apolipoprotein A I (APOA1) Mouse Monoclonal Antibody [Clone ID: 2D6-3B2-7C2]

CAT#: TA383738

ApoA1 (2D6) Mouse monoclonal Antibody

Product Images

Western blot analysis of ApoA1 (2D6) in HepG2 and Human serum lysates using ApoA1 (2D6) antibody.

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  Western blot analysis of ApoA1 (2D6) in HEK293T cells transfected with the pCMV6ENTRY control and pCMV6ENTRY APOA1 cDNA using ApoA1 (2D6) antibody

Specifications

Product Data

• Clone Name: 2D6-3B2-7C2
• Applications: WB
• Recommended Dilution: WB: 1/500-1/2000
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Purified recombinant fragment of human APOA1 expressed in E. Coli.
• Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.03% Proclin 300, pH 7.3.
• Concentration: lot specific
• Purification: Ascitic Fluid
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: 25kDa
• Gene Name: apolipoprotein A1
• Database Link:
  Entrez Gene 335 Human
  UniProt ID P02647
• Background: Swiss-Prot Acc.P02647.APOA1: apolipoprotein A-I, it is the major protein component of high density lipoprotein (HDL) in plasma. The protein promotes cholesterol efflux from tissues to the liver for excretion, and it is a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters. Defects in the Apolipoprotein A I gene are associated with HDL deficiency and Tangier disease. The therapeutic potential of apoA-I has been recently assessed in patients with acute coronary syndromes, using a recombinant form of a naturally occurring variant of apoA-I. The availability of recombinant normal apoA-I should facilitate further investigation into the potential usefulness of apoA-I in preventing atherosclerotic vascular diseases.
• Synonyms: Apo-AI; ApoA-I; MGC117399; OTTHUMP00000069346; OTTHUMP00000069347; OTTHUMP00000069348