AGR2 Rabbit Polyclonal Antibody

CAT#: TA319825

Rabbit Polyclonal AGR2 Antibody

Product Images

Western blot analysis of AGR2 in Hela cell lysate with AGR2 antibody at (A) 1 and (B) 2 ug/mL

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  Immunohistochemistry of AGR2 in human small intestine tissue with AGR2 antibody at 5 ug/mL.

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  Immunofluorescence of AGR2 in human small intestine tissue with AGR2 antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1 - 2 ug/mL
• Reactivities: Hamster
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Rabbit polyclonal AGR2 antibody was raised against a 17 amino acid peptide near the amino terminus of human AGR2.
• Formulation: AGR2 Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: AGR2 Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 19 kDa
• Gene Name: anterior gradient 2, protein disulphide isomerase family member
• Database Link:
  NP_006399
  Entrez Gene 10551 Human
  UniProt ID O95994
• Background: AGR2 Antibody: AGR2 (anterior gradient protein 2) and AGR3 are members of the anterior gradient homolog family. They are secreted cytoplasmic proteins which are involved in metastasis induction and p53 tumour supressor inhibition. They may serve as molecular markers and potential therapeutic targets for hormone-responsive breast tumours. AGR2 is ubiquitously expressed with upregulated expression in prostate cancer, breast cancer, lung cancer, renal carcinomas and endometrial carcinomas. AGR2 expression is positively correlated with that of the estrogen receptor (ER) and is negatively correlated with that of the epidermal growth factor receptor (EGFR).
• Synonyms: AG2; GOB-4; HAG-2; HEL-S-116; PDIA17; XAG-2

Reference Data

• Protein Families: Secreted Protein