SNVsMgp1 Rabbit Polyclonal Antibody

CAT#: TA160112

Rabbit Polyclonal Anti-Sin Nombre Virus Glycoprotein 1 Antibody

Specifications

Product Data

• Recommended Dilution: ELISA: 1 ug/mL
• Reactivities: Sin Nombre orthohantavirus
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Sin Nombre virus glycoprotein 1 antibody was raised against a 19 amino acid peptide near the amino terminus of the Sin Nombre virus glycoprotein.
• Formulation: PBS containing 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Background: Sin Nombre virus (SNV) is a rodent-borne hantavirus of the family Bunyaviridae, an enveloped, negative-sense RNA viruses with a tripartite genome that can cause hantavirus pulmonary syndrome (HPS) (1). Hantavirus glycoprotein precursor (GPC) is posttranslationally cleaved into two glycoproteins G1 (Gn) and G2 (Gc). The G1 glycoprotein is is thought to be degraded by the host autophagy machinery, and this autophagic clearance is required for efficient virus repliaction (2).