SARS-CoV Spike Protein Rabbit Polyclonal Antibody

CAT#: TA160053

Rabbit Polyclonal Anti-SARS-CoV Spike Protein Antibody

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ELISA Test Antibodies: SARS-CoV Spike Antibody, TA160053 (1 μg/mL). A direct ELISA was performed using immunogen as coating antigen and the anti-SARS-CoV Spike antibody as the capture antibody. Secondary: Goat anti-rabbit IgG HRP conjugate at 1:20000 dilution. Detection range is from 2 ng/mL to 1000 ng/mL.

Specifications

Product Data

• Recommended Dilution: ELISA: 1 ug/ml
  The antibody will detect 5 ng of free peptide at 1 μg/ml.
• Reactivities: SARS-CoV
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The antibody was raised against a peptide corresponding to 15 amino acids between aa 650-700 near the center of SARS-CoV Spike glycoprotein.
  Predicted reactivity based on immunogen sequence to SARS-CoV2 Spike protein unlikely: identity 40%, homology 56%.
• Formulation: PBS containing 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Database Link:
  UniProt ID P59594
• Background: SARS Spike Antibody: A novel coronavirus has recently been identified as the causative agent of SARS (Severe Acute Respiratory Syndrome). Coronaviruses are a major cause of upper respiratory diseases in humans. The genomes of these viruses are positive-stranded RNA approximately 27-31kb in length. SARS infection can be mediated by the binding of the viral spike protein, a glycosylated 139 kDa protein and the major surface antigen of the virus, to the angiotensin-converting enzyme 2 (ACE2) on target cells. This binding can be blocked by a soluble form of ACE2.