CRYAA2 Mouse Monoclonal Antibody [Clone ID: c9F2]
CRYAA2 mouse monoclonal antibody, clone c9F2, Purified
Western blot (1:500 - 1:2,000), recommended starting dilution 1:1000.
|Reactivity||Human, Mouse, Rat|
|Immunogen||Recombinant human Crystallin alpha A (1-173aa) purified from E. coli|
|Specificity||The antibody recognizes human , rat and mouse Crystallin-alpha A.
Other species not tested.
|Formulation||PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol
State: Liquid purified Ig fraction
|Purification||Protein-G affinity chromatography|
|Background||Crystallins alpha are composed of two gene products; alpha A and alpha B, for acidic and basic, respectively. crystallins alpha can be induced by heat shock and are members of the small heat shock protein (sHSP also known as the HSP20). They act as molecular chaperones and hold them in large soluble aggregates. These heterogeneous aggregates consist of 30-40 subunits; the alpha A and alpha B subunits have a 3:1 ratio, respectively. Two additional functions of alpha crystallins are an autokinase activity and participation in the intracellular architecture. The expression of alpha-A is preferentially restricted to the lens cell.|
|Synonyms||CRYAA, HSPB4, Heat shock protein beta-4|